Evaluation of Family History, Antioxidant Intake and Activity Level as Indicators For Chronic Disease In A Healthy Young Population

Document Type

Article

Publication Date

2015

Abstract

We recruited 24 men and 26 women (18-30 y) to evaluate whether family history, activity level, or dietary intake correlated with dyslipidemias, blood pressure or blood glucose levels in this young population. The mean values for plasma triglycerides (72.5 ± 29.9 mg/dL), LDL-cholesterol (LDL-C) (75.6 ± 24.4 mg/dL) HDL-cholesterol (64.9 ± 18.9 mg/dL), glucose (92.2 ± 6.6 mg/dl), systolic (112.0 ± 12.4 mmHg) and diastolic blood pressure (72.9 ± 7.0 mmHg), body mass index (23.3 ± 3.1 kg/m2), and waist circumference (81.3 ± 6.5 cm) were within a healthy range. However, 32% of individuals (n=16, 11 male and 5 female) had either elevated LDL-C (> 100 mg/dL), or at least one parameter associated with metabolic syndrome. Family history indicated that 60% of the participants could be at risk for cancer, 46% for heart disease, and 38% for diabetes. For all subjects, number of active minutes per week was negatively correlated with LDL-C (r = -0.339, P < 0.05) and triglycerides (r = -0.41, P < 0.01), whereas HDL-cholesterol was positively correlated with intake of the carotenoids, lutein and zeaxanthin (r = 0.339, P < 0.05).Systolic (r = -0.277, p< 0.05) and diastolic blood pressure (r = -0.307, P < 0.05) negatively correlated with dietary lutein and zeaxanthin. These results imply that increased physical activity and a diet high in antioxidants favorably affect biomarkers for heart disease and diabetes, suggesting that lifestyle factors may protect against disease risk in this population characterized as having a family history of chronic disease.

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Copyright: © 2015 Maria Luz Fernandez., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Published by ECronicon

Publication Title

EC Nutrition

Published Citation

Fernandez, Maria Luz and Marcela Vergara-Jimenez, Amanda Missimer, Diana M DiMarco, Catherine J Andersen, Ana Gabriela Murillo. "Evaluation of Family History, Antioxidant Intake and Activity Level as Indicators For Chronic Disease In A Healthy Young Population." EC Nutrition, 1.4 (2016): 164-173.

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