Chelated iridium (III) bis-carbene complexes as air-stable catalysts for transfer hydrogenation

Authors

Martin Albrecht
John R. Miecznikowski, Fairfield UniversityFollow
Amanda Samuel
Jack W. Faller
Robert H. Crabtree

Document Type

Article

Publication Date

2002

Abstract

The new air-stable and moisture-insensitive Ir catalysts for efficient transfer hydrogenation of ketones contain a chelating bis(N-heterocyclic carbene) ligand. Most other hydrogen transfer catalysts show activity Rh > Ir, but we find Ir > Rh for these cases. Tuning of the ligand wingtip substituents, R, can greatly increase catalyst activity (R = neopentyl) or selectivity (R = isopropyl). Reactivity studies and isotopic labeling are consistent with a monohydride mechanism for the hydrogen transfer.

Comments

Copyright 2002 American Chemical Society

A link to full text has been provided for authorized users.

Publication Title

Organometallics

Repository Citation

Albrecht, Martin; Miecznikowski, John R.; Samuel, Amanda; Faller, Jack W.; and Crabtree, Robert H., "Chelated iridium (III) bis-carbene complexes as air-stable catalysts for transfer hydrogenation" (2002). Chemistry & Biochemistry Faculty Publications. 38.
https://digitalcommons.fairfield.edu/chemistry-facultypubs/38

Published Citation

Albrecht, M.; Miecznikowski, J.R.; Samuel, A.; Faller, J.W.; Crabtree, R.H. “Chelated iridium (III) bis-carbene complexes as air-stable catalysts for transfer hydrogenation.” Organometallics, 2002, 21 (17), 3596-3604. doi:10.1021/om020338x.

DOI

10.1021/om020338x

Peer Reviewed